D2: Digital, FAIR, and high-quality research data

D2: Digital, FAIR, and High-Quality Research Data

Research data on the safety of advanced materials is generated in a multidisciplinary environment and includes data from material characterisation to toxicology. In order to make this data and the associated metadata (re-)usable for researchers and also manufacturers and regulatory authorities, it is important that the information is structured, coordinated and available in digital form. This is also increasingly required by funding bodies (Open Science, Open Data) and publishers and is increasingly expected as part of good scientific practice. Reproducibility of results and traceability of scientific data are thus improved.

In the context of safety assessment of advanced materials, data-driven concepts such as safe-by-design 1, 2, Adverse Outcome Pathway (AOP) 3, computational modelling and meta-analyses promote the development of new and safer materials. Partners of the research network are involved in further projects that are advancing this topic, such as: NanoS-QM 4, NFDI4Chem, and the Leibniz ScienceCampus „Digital Transformation in Research“.

    Our aim is to develop a research data infrastructure that:

  • meets the requirements of research on safety of advanced materials and
  • supports a data management along the FAIR-principles.

This must necessarily start at different points and integrate into existing national (NFDI) and international initiatives (EOSC). Development is taking place in parallel to the activities of the research alliance within the framework of spin-off projects.

Involved Partners


Link zur Seite 'Partnerinstitute'#INM

Link zur Seite 'Partnerinstitute'#IPF

Links to 'Partner institutes'#DWI

Links to 'Partner institutes'#IWT

Links to 'Partner institutes'#IUF

Links to 'Partner institutes'#IPB

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Links to 'Partner institutes'#IfADo
References and Previous Works
  1. Dekkers S, Wijnhoven SWP, Braakhuis HM, Soeteman-Hernandez LG, Sips AJAM, Tavernaro I, Kraegeloh A, Noorlander CW, Safe-by-Design part I: Proposal for nanospecific human health safety aspects needed along the innovation process. NanoImpact 18 (2020) 100227. https://doi.org/10.1016/j.impact.2020.100227
  2. Tavernaro I, Dekkers S, Soeteman-Hernández LG, Herbeck-Engel P, Noorlander C, Kraegeloh A, Safe-by-Design part II: A strategy for balancing safety and functionality in the different stages of the innovation process. NanoImpact 24 (2021) 100354. https://doi.org/10.1016/j.impact.2021.100354.
  3. Boyes WK, van Thriel C, Neurotoxicology of nanomaterials. Chem Res Toxicol 33 (2020) 1121. https://dx.doi.org/10.1021/acs.chemrestox.0c00050
  4. Binder K, Bonatto Minella C, Elberskirch L, Kraegeloh A, Liebing J, Petzold C, Razum M, Riefler N, Schins R, Sofranko A, van Thriel C, Unfried K. Discussion on Existing Standards and Quality Criteria in Nanosafety Research – Summary of the NanoS-QM Expert Workshop. https://doi.org/10.5281/zenodo.4584789

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